Tabex® is a natural product based on cytisine which, due to its structural similarity to nicotine, binds to various types of nicotinic receptors: its binding affinity to α4β2 is very high (seven times that of nicotine) and it acts as a partial agonist on them.
During abstinence, in the absence of the full-agonist nicotine, cytisine sub maximally activates receptors and allows some dopamine release in reward circuits, controlling withdrawal symptoms and craving. In the presence of nicotine (if the subject smokes) it transforms into a competitive antagonist by shifting the dose-response curve to the right: this reduces the central effects of nicotine, interferes with the receptor sensitisation/desensitisation cycle, counteracts reinforcing effects and makes smoking taste unpleasant.
Tabex® offer, benefits:
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Tabex Sopharma - acts very effectively on smoking withdrawal symptoms |
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Tabex Sopharma - treatment duration of only 25 days |
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Tabex Shop - shipping within 10 working days in all Europe |